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Kumari, Kanya
- Glycemic Control and Pulmonary Function Tests in Type 2 Diabetes Mellitus Patients: do they Correlate?
Authors
1 Dept. of Physiology, J.S.S. Medical College, Mysore, Karnataka, IN
2 Dept of Medicine, J.S.S. Medical College, Mysore, Karnataka, IN
Source
Indian Journal of Public Health Research & Development, Vol 4, No 2 (2013), Pagination: 124-128Abstract
Diabetes is a multisystem disorder accompanied by widespread biochemical, morphological and functional abnormalities which may precipitate certain complications that affect the renal, cardiovascular, neural system, liver, skin and tissues like collagen and elastic fibers. This study was undertaken to find out the correlation between glycemic control and pulmonary function tests(PFT).
Study group consists of 90 patients who were age, sex, height and weight matched. PFT were measured by Medspiror. Fasting blood sugar(FBS),Postprandial blood sugar(PPBS), Glycosylated haemoglobin (HbA1C) levels were recorded. The data was statistically analysed. It showed that with the worsening of glycemic control there was decrease across all the PFT parameters.
Normal lung mechanisms and gas exchange are influenced by integrity of pulmonary connective tissue and microvasculature. Hyperglycemia causes glycosylation of lung collagen and hence less compliant lung parenchyma leading to restrictive lung changes.
Keywords
Glycemic Control, Pulmonary Function Tests, Glycosylation, Restrictive Lung Pathology
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